产品货号：
Z22141
中文名称：
NUMB抗体
英文名称：
Anti-NUMB Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-NUMB Antibody |
| 指标别名 | h Numb;NUMB;numb homolog (Drosophila);Protein numb homolog;Protein S171;S171 |
| 克隆性 | Polyclonal |
| 检验物种 | human,monkey,mouse,rat |
| 应用范围 | WB,IHC,FCM,ELISA |
| 基因名称 | NUMB |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human NUMB(194-220aa SFRVTTATEQAEREEIMKQMQDAKKAE),different from the related mouse and rat sequences by one amino acid. |
| 实际分子量 | 71KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | Protein numb homolog is a protein that in humans is encoded by the NUMB gene.It is mapped to 14q24.2 to q24.3.The encoded protein,whose degradation is induced in a proteasome-dependent manner by MDM2,is a membrane-bound protein that has been shown to associate with EPS15,LNX1,and NOTCH1.The primary function of Numb in cell differentiation is as an inhibitor of Notch signaling which is essential for maintaining self-renewal potential in stem and progenitor cells.Numb also plays a crucial role in asymmetrical cell division during development,allowing for differential cell fate specification in the central and peripheral nervous systems.What’s more,the numb gene protein product controls binary cell fate decisions in the peripheral and central nervous systems of both invertebrates and mammals during neurogenesis. |
| Uniprot ID | P49757 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | numb homolog (Drosophila) |
| 蛋白名全称 | Protein numb homolog |
| 推荐稀释比 | Western blot (WB) 1:500～2000 Immunohistochemistry in paraffin section (IHC) 1:50～400 Flow cytometry (FCM) 1～3μg/1×106 cells (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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